About Us

BioMapping 1000

Comprehensive anatomy of large tissue at submicron level

Based on MOST technology, BioMapping 1000 can simultaneously visualize complex information without specific labelling. Nissl staining and Golgi staining is combined to enable the imaging to take place. This means that the instrument provides different signals with distinct grey values and morphologies. This ensures easy extraction and reconstruction of regions within the whole tissue.
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Be Meticulous

Sectioning-Imaging Mode

Innovative way to acquire whole brain imaging at single neuron level

Combine ultra-thin sectioning and high-contrast imaging in a unique,high-throughput way.
You are also able to enable visualization of synaptic-connection-related dendritic spines and axon boutons over the brain wide scale at the complete single neuron level.

Simple Experience

Isotropic resolution

Demonstrate 3D data in any direction

Unlock isotropic resolution throughout the entire specimen.Self-registration of the whole-brain imaging data facilitates reconstruction of the whole tissue morphology in the most authentic way in 3D.


Resin embedding

Sample preparation made easy

Our optimised resin embedding method maintains the original shape of sample, preserves and enhances the fluorescence signal. The method can easily applied to various sample types including intact mouse, ferret and macaque brains as well as other organs. 
You can also combine this method with other raditional staining methods such as Golgi, Nissl and HE staining.

Full Coverage

Real-time staining

Rapid staining to maximize performance and efficiency

Simultaneously acquire labelled neural structures and cytoarchitecture reference using a real-time staining approach. This facilitates precise tracing of long-range projections and accurate locating of individual neurons in the whole brain.

BioMapping series systems are based on Micro-Optical Sectioning Tomography (MOST) technology. MOST technology enables easy sample preparation, high image resolution & fast data acquisition. Our unique and patented combination of sample sectioning and optical imaging enables neuroscientists worldwide to easily investigate whole-brain neuron projections and establish a standardized anatomical atlas.
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Whole-brain connectome

Precise tracing of whole-brain neuronal projections at single-cell resolution

Alzheimer’s disease

Depicting Aβ plaques, somata, nerve processes and tracts, and blood vessels from a new cross-scale view

Neuron morphology

Subcellular, synaptic-connection-related dendritic spines and axon boutons over the brain-wide scale

Organ & tissue

Revealing the sophisticated anatomy of a wide range of intact organs and large tissue

Protein & particle distribution

Mapping the distribution of particles at 3D, in-situ, and single-particle level

Vessel analysis

Visualizing the entire vascular system from large vessels down to smallest capillaries
Undertaking fMOST imaging can be a tricky process but we are here to make the whole process easier and to help your next project become the success it deserves to be. We provide comprehensive support from sample preparation all the way down to sample analysis. With our help, there is no need to establish specific working environments or to spend lots of time and money on learning each step of the fMOST imaging process.
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